DNA-In® Neuro

Formulated Specifically for Neurons 
Developed by the co-inventors of the early Lipofectamine® products, DNA-In® Neuro Transfection reagent was formulated from a novel chemistry for maximum transfection efficiency in neurons. In side-by-side assays with top competitor reagents significantly higher transfection efficiencies are consistently observed when DNA-In® Neuro is used to transfect primary cortical, hippocampal or forebrain neurons. Moreover, with low cytotoxic effect DNA-In® Neuro supports neuronal survival and neurite extension post-transfection.



Feature Benefits:
  • Higher Transfection Efficiency - Two-fold or greater improvement in efficiency over competing transfection reagents
  • Exceptionally Low Toxicity - Maximum post-transfection neuron viability critical for performing assays on healthy,  uncompromised transfected neurons.
  • Highly Robust Performance – Produces consistent and reproducible results.
  • Quick and Easy-to-Use – An easy to follow, single-tube reagent protocol for great results on the very first try

SUPERIOR TRANSFECTION EFFICIENCY vs. LEADING COMPETITOR REAGENTS 
DNA-In® Neuro Transfection Reagent is a new transfection reagent that consistently produces high transfection efficiencies in neurons, typically achieving a 2-fold or better improvement in efficiency over the competing reagents currently available, including Lipofectamine® 2000 and NeuroFECT™. Moreover, DNA-In® Neuro enables neurons to be efficiently transfected with minimal toxicity to support healthy post-transfected neurons, critical for performing assays on uncompromised transfected cells.

DNA-In® is a Molecular Transfer, Inc trademark. 
Lipofectamine is a Thermo Fisher Scientific Inc. product. 
NeuroFECT™ is a Genlantis product.

References
  1. Tsai HD, Wu JS, Kao MH, Chen JJ, Sun GY, Ong WY, Lin TN. (2016) Clinacanthusnutans Protects Cortical Neurons Against Hypoxia-Induced Toxicity by Downregulating HDAC1/6 Neuromolecular Med May 10.
  2. Gervasi NM, Scott SS, Aschrafi A, Gale J, Vohra SN, MacGibeny MA, Kar AN, Gioio AE, Kaplan BB. (2016)  The Local Expression and Trafficking Of Tyrosine Hydroxylase mRNA In The Axons Of Sympathetic Neurons RNA 22:1–13.