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Meropenem Trihydrate
Product ID: M5600

Introduction

Description: A broad spectrum antibiotic that has a high affinity for cell wall-synthesizing enzymes. It is a beta-lactam and belongs to the subgroup of carbapenem. The spectrum of action includes many gram-positive and gram-negative bacteria (including Pseudomonas) and anaerobic bacteria.

Synonyms: Mesalazine; Mesalamine; Meropenemum

Solubility Water (~5 mg/mL)
Physical Form Solid
Storage Temp. -20 C
Other Notes Plant Tissue Culture Tested
CAS NUMBER 119478-56-7
Formula Weight 437.51
Formula C17H25N3O5S · 3H2O
Synonyms Mesalazine; Mesalamine; Meropenemum
Storage Temp. -20°C
Tariff Code 2941.90.5000
   
No information available

M5600 Meropenem

Properties
Form: Powder
Appearance: White to Light Yellow
Application: Antibiotic
Solubility: Water
Storage Temp: 2-6°C
Typical Working Concentration: Varies by application. Concentration should be determined by end user
Other Notes: Plant Tissue Culture Tested

Application Notes
A broad spectrum antibiotic that has a high affinity for cell wall-synthesizing enzymes. Meropenem is very effective because it resists inactivation by the majority of microbial LACTB (β-lactamases). It is a beta-lactam and belongs to the subgroup of carbapenem. Meropenem is bactericidal except against Listeria monocytogenes where it is bacteriostatic. It inhibits bacterial wall synthesis like other beta-lactam antibiotics. In contrast to other beta-lactams, it is highly resistant to degradation by beta-lactamases or cephalosporinases.

The spectrum of action includes many gram-positive and gram-negative bacteria (including Pseudomonas) and anaerobic bacteria.

Konagaya et al. note the successful elimination of Agrobacterium from Cryptomeria japonica (Japanese cedar) cultures using a concentration of 10 mg/L of Meropenem without observing phytotoxic effects.

References
Kayser, F H., et al., (1989) Activity of meropenem, against gram-positive bacteria. The Journal of antimicrobial chemotherapy. 24: 101-12. Konagaya, K. I., Kurita, M., & Taniguchi, T. (2013). High-efficiency Agrobacterium-mediated transformation of Cryptomeria japonica D. Don by co-cultivation on filter paper wicks followed by meropenem treatment to eliminate Agrobacterium. Plant Biotechnology, 30(5), 523-528.