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Product ID: C252


Description: Chloramphenicol is derived from Streptomyces venezuelae and has a broad spectrum of activity against gram-positive and gram-negative bacteria. It is often used for selection in molecular biology with the cyt B gene.

See product info sheet for more information.

Solubility Ethanol at 50 mg/mL; The Merck Index indicates solubility at 2.5 mg/mL in water
Grade USP
Physical Form Solid
Storage Temp. Room Temperature
UPC / SKU C252
CAS NUMBER 56-75-7
Formula Weight 323.13
Formula C11H12Cl2N2O5
Synonyms 2,2-Dichloro-N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
Storage Temp. Room Temperature
Tariff Code 2941.40.0000
Risk Info (R) 42/43-45
Safety Info (S) 45-36/37/39
No information available

C252 Chloramphenicol

Synonym: [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4- nitrophenyl)ethyl]acetamide, Chloromycetin, CAP
CAS: 56-75-7
Formula: C11H12Cl2N2O5
Molecular Wt: 323.13
Form: Powder
Appearance: Off-white to Yellow
Application: Antibiotic
Solubility: Soluble in water at up to 2.5 mg/mL per the Merck Index. More highly soluble in ethanol. Consult the certificates of analysis for lot-specific solubility information
Storage Temp: Room Temperature
Storage Temp of Stock Solution: Store at 2-6°C for 30 days. Protect from light.
Typical Working Concentration: Varies by application, should be determined by end user
Other Notes: Derived from Streptomyces venezuelae. Plant Tissue Culture Tested

Application Notes
Chloramphenicol is derived from Streptomyces Venezuelae and has a broad spectrum of activity. It is often used for bacterial selection in molecular biology. Chloramphenicol is effective against grampositive and gram-negative bacteria. It functions by binding to the 50S ribosomal unit to prevent aminoacyl tRNA from binding to the ribosome which prevents elongation of protein chain.

Merck 13, 2087 Sweetman SC (ed), Martindale: The Complete Drug Reference 35. China: Pharmaceutical Press, 2007