Introduction
Description: CHAPS is a non-denaturing, zwitterionic detergent often used in the solubilization and purification of membrane proteins. It does not exhibit a net charge between pH 2 and 12, making it useful for ion exchange chromatography and isoelectric focusing as well.
3-[(3-chloamidopropyl)dimethyl-ammonio]-1-propanesulfonate
| Solubility |
Water |
| Physical Form |
Solid |
| Storage Temp. |
Room Temperature |
| UPC / SKU |
C526 |
| CAS NUMBER |
75621-03-3 |
| Formula Weight |
614.89 |
| Formula |
C32H58N2O7S |
| Synonyms |
3-[(3-chloamidopropyl)dimethyl-ammonio]-1-propanesulfonate |
| Storage Temp. |
Room Temperature |
| Tariff Code |
2924.29.9500 |
| Risk Info (R) |
20/22-36/37/38 |
| Safety Info (S) |
22-26-36 |
No information available
C526 CHAPS
| Properties |
|---|
| Form: |
Powder |
| Appearance: |
White to Off-White |
| Application: |
Detergent |
| Solubility: |
Soluble in water |
| Typical Working Concentration: |
Varies with application; should be determined by end user |
| Storage Temp: |
|
| Storage Temp of Stock Solution: |
N/A |
Application Notes
CHAPS is a non-denaturing, zwitterionic detergent often used in the solubilization and purification of membrane proteins. It does not exhibit a net charge between pH 2 and 12, making it useful for ion exchange chromatography and isoelectric focusing as well.
References
Anglister, J, S Grzesiek, H Ren, C B. Klee, A Bax (1993) Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS. Journal of Biomolecular NMR 3:1, pp. 121-126.
