Introduction
Description:
INA is employed in the biological study of plant pathogen resistance. It can induce a systemic acquired resistance (SAR) response in plants, 2,6-Dichloropyridine-4-carboxylic Acid
| Solubility |
Methanol; 1% Ethanol |
| Physical Form |
Solid |
| Storage Temp. |
-20 °C |
| UPC / SKU |
D2181 |
| CAS NUMBER |
5398-44-7 |
| Formula Weight |
192.00 |
| Formula |
C6H3Cl2NO2 |
| Synonyms |
2,6-Dichloropyridine-4-carboxylic Acid; INA |
| Storage Temp. |
-20 °C |
| Tariff Code |
2933.39.6190 |
No information available
D2181 2,6-Dichloroisonicotinic Acid
| Synonyms: |
2,6-Dichloropyridine-4-carboxylic Acid; INA |
| CAS: |
5398-44-7 |
| Formula: |
C6H3Cl2NO2 |
| Mol. Weight: |
192.00 |
| Properties |
|---|
| Form: |
Powder |
| Appearance: |
White to Off-white to Faint Yellow to Beige |
| Application: |
Plant Defense |
| Solubility: |
Methanol, Ethanol |
| Typical Working Concentration: |
Varies: 0.7 mM (Vernooij et al., 1995) 0.53 to 530 µM (Schweizer et al., 1997) |
| Storage Temp: |
-20°C |
| Other Notes: |
Plant tissue culture tested |
Application Notes
2,6-Dichloroisonicotinic acid was the first synthetic chemical found to induce SAR (systemic acquired response) (Ward et al., 1991). The mechanism by which this works is 2,6- Dichloroisonicotinic Acid binds the SA-binding protein/catalase and inhibits its enzymatic activity (Conrath et al., 1995)
References
Conrath U, Chen Z, Ricigliano JR, Klessig DF (1995) Two inducers of plant defense responses, 2,6-dichloroisonicotinec acid and salicylic acid, inhibit catalase activity in tobacco. PNAS 92(16):7143–7147.
References (cont.)
Schweizer P, Buchala A, Métraux J (1997). Gene-expression patterns and levels of jasmonic acid in rice treated with the resistance inducer 2,6-dichloroisonicotinic acid. Plant Physiol. 115, 61–70. Vernooij B, Friedrich L, Ahl Goy P, Staub T, Kessmann H, Ryals J, (1995) 2,6- Dichloroisonicotinic acid-induced resistance to pathogens without the accumulation of salicylic acid. Molecular Plant–Microbe Interactions 8(2), pp.228-34. Ward ER, Uknes SJ, Williams SC, Dincher SS, Wiederhold DL, Alexander DC, Ahl-Goy P, Métraux JP, and JA Ryals. 1991. Coordinate Gene Activity in Response to Agents That Induce Systemic Acquired Resistance. The Plant Cell 3(10) 1085-1094.
