Introduction
Description: Erythromycin is a broad-spectrum macrolide antibiotic produced by a strain of Streptomyces erythreus. Its mode of action is to inhibit protein synthesis.
See product info sheet for more information.
Solubility |
Water |
Grade |
USP |
Physical Form |
Solid |
Storage Temp. |
Room Temperature |
UPC / SKU |
E344 |
CAS NUMBER |
114-07-8 |
Formula Weight |
733.92 |
Formula |
C37H67NO13 |
Storage Temp. |
Room Temperature |
Tariff Code |
2941.50.0000 |
Risk Info (R) |
42/43-36 |
Safety Info (S) |
22-24/25-36/37/39 |
No information available
E344 Erythromycin
Synonym: |
Erythromycin A |
CAS: |
114-07-8 |
Formula: |
C37H67NO13 |
Molecular Wt: |
733.92 |
Properties |
Form: |
Powder |
Appearance: |
White to Off-white Powder |
Application: |
Plant Tissue Culture Antibiotic |
Solubility: |
PhytoTechnology Laboratories® tests solubility at 10 mg/mL in ethanol. Per the Merck Index, erythromycin is soluble in water at 2 mg/mL |
Storage Temp: |
Room Temperature |
Other Notes: |
This product is slightly hygroscopic. |
Application Notes
Erythromycin is a broad-spectrum macrolide antibiotic produced by a strain of Streptomyces erythreus. Its mode of action is to inhibit protein synthesis by binding to the 50S ribosome subunit and blocking its transpeptidation.2 Erythromycin is effective against most Gram-positive cocci and bacilli and some Gram-negative bacteria;3 however, its activity is enhanced in alkaline condition at approximate pH 8.5 for Gram-negative bacteria.2
It has been reported that the minimum inhibitory concentration of erythromycin for Staphylococci epidermidis is 8 to greater than 32 µg/mL and Staphylococci aureus is 0.12 to greater than 128 µg/mL.3
Please Note: While PhytoTechnology Laboratories® tests each lot of this product with two or more plant cell/ tissue culture lines, it is the sole responsibility of the purchaser to determine the appropriateness of this product for the specific plants that are being cultured and applications that are being used.
References
1. Merck 13, 3714
2. Martindale: The Complete Drug Reference, 35th ed., Paul S. Blake, Ed. (Royal Pharmaceutical Society, 2007), p. 240.
3. Sultana, Najma, M. Saeed Arayne and Rizwana Sabri. 2005. Erythromycin synergism with essential and trace elements. Pakistan Journal of Pharmaceutical Sciences. Vol. 18, No. 2. Pp 35-39