M-MLV Reverse Transcriptase

Moloney Murine Leukemia Virus Reverse Transcriptase (M-MLV RT) is a RNA-directed DNA polymerase that can synthesize a complementary DNA (cDNA) strand from a primer hybridized to either RNA or single stranded DNA as a template. M-MLV Reverse Transcriptase is capable of synthesizing DNA longer than 5 kb from messenger RNA. RNase H activity of M-MLV reverse transcriptase is weaker than that of Avian Myeloblastosis Virus (AMV) reverse transcriptase.

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Literature References:

• Hongmarn Park, et al(2013). Exploring sRNA-mediated gene silencing mechanisms using artificial small RNAs derived from a natural RNA scaffold in Escherichia coli. Nucl Acids Res. 41(6), 3787-3804
• Hyemin Kim, et al(2011). Epigenetic signatures and temporal expression of lineage-specific genes in hESCs during differentiation to hepatocytes in vitro. Hum. Mol. Genet 20(3), 401-412
• Jung Wook Yang, et al(2011). Whitefly infestation of pepper plants elicits defence responses against bacterial pathogens in leaves and roots and changes the below-ground microflora. Journal of Ecology 99,46-56
• Huiseok Chae, et al(2010). Rho-dependent termination of ssrS (6S RNA) transcription in Escherichia coli: implication for 3' processing of 6S RNA and expression of downstream ygfA (putative 5-formyl tetrahydrofolate cyclo-ligase). J Biol Chem. 286, 114-122
• Hye-Ju Son, et al(2012). Negative Regulation of JAK2 by H3K9 Methyltransferase G9a in Leukemia. Mol. Cell. Biol. 32, 3681-3694